When you get a chance to be Venom, pick him. Then play untill you get to the ATM machine. Press your power hits. Note: it will make you enter a secret room.
When facing Doppleganger in the 3rd level with Spider-Man, keep hiting the water tank. The tank will fall and you will be able to carry it. Other than the continue that you will find under the tank, you can throw it at Doppleganger to kill him. To make it easier, knock Doppleganger down before you hit the tank!
At level 2 (Climb) with Spider-man, go to the window at the very right. Now, climb on top of the window. Then, jump and hit the window while in mid air. You'll enter a secret room.
At the very first level of the game, go to the newspaper stand. You'll find a newspaper on top of it a health power-up. Crawl on top of the stand. You'll find a life power-up. If you didn't find it, then maybe it was on another wall because I remember that it was there.
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